Acadesine 10mg*100pills/bottle 99% Purity CAS 2627-69-2 SARMs Raw Powder Aicar Tablets For Muscle Mass

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Detailed Product Description

Keywords:Aicar
Appearance:White Powder
Shipping Method:FEDEX, TNT, DHL, UPS, HK EMS
Delivery Time: Within 24 Hours After The Payment
MOQ:10g
Grade Standard:Medicine Grade
Purity:99%min
High Light:bodybuilding legal steroids, fat burning sarms

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Product Detail

Product Tags

Acadesine 10mg Product Details

Other name: Acadesine,AICAR,AICA-RIBOSIDE,AMPK,Z-RIBOSIDE
CAS: 2627-69-2
EINECS: 220-097-5
Molecular Formula: C9H14N4O5
Molecular Weight: 258.23
Assay: 99%
Apperance: White or off-white powder.
Usage: Pharmaceutical intermediates. For the treatment of cardiovascular diseases

Aicar is a cell permeable activator of AMP-activated protein kinase (AMPK), a metabolic master regulator that is activated in times of reduced energy availability (high cellular AMP:ATP ratios) and serves to inhibit anabolic processes. In vivo, pharmacologic activation of AMPK with Aicar mimics exercise and triggers insulin-independent glucose uptake by skeletal muscle.

Acadesine 10mg Function

AICAR strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK, and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

AMP-activated protein kinase (AMPK) functions as a metabolic sensor that regulates lipid and glucose metabolism to maintain cellular energy homeostasis and to protect against metabolic stress.AICAR is a selective activator of AMPK in both hepatocytes and adipocytes. At 0.5 mM it inhibits the synthesis of fatty acids and sterols and inactivates HMG-CoA reductase in rat hepatocytes.AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of controls and reduces GLUT4 translocation 2.5-fold in 3T3-L1 adipocytes. It also blocks the expression of pro-inflammatory cytokines (TNF-α/IL-1β and IL-6), iNOS, COX-2, and MnSOD genes in glial cells and macrophages by inhibiting NFκB and C/EBP pathways.

Acadesine 10mg Application

Aicar (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR& alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).
The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

Acadesine 10mg COA

Item	Specification	Result
Appearance	White powder	Complies
Related substance (HPLC)	Total impurity ≤0.5% Max single impurity ≤0.1%	0.2% 0.06%
Odor	Characteristic	Complies
Assay	99%	99.8%
Sieve analysis	100% pass 80 mesh	Complies
Loss on Drying Residue on Ignition	≤1.0% ≤1.0%	0.12% 0.09%
Heavy Metal	<10ppm	Complies
As	<0.1ppm	0.05ppm
Pb	<0.1ppm	0.05ppm
Cd	<0.1ppm	0.05ppm
Residual Solvents	<100ppm	Complies
Residual Pesticide	Negative	Complies
Microbiology
Total Plate Count	<1000cfu/g	Complies
Yeast & Mold	<100cfu/g	Complies
E.Coli	Negative	Complies
Salmonella	Negative	Complies

Contact Us

Hjtc (Xiamen) Industry Co., Ltd.

Xiamen Huayongjian Biotechnology Co., Ltd.

Contacts: June & Eason

Whatsapp:+8618206063252; +8618759200098

E-mail: june@steroidpowder-hjtc.com;

eason@steroidpowder-hjtc.com

Web site:https://www.steroidpowder-hjtc.com/
http://www.safeststeroid.com/
http://www.glassviallabels.com/
https://hjtc-printing.en.made-in-china.com/

Company Profile

Hjtc (Xiamen) Industry Co., Ltd. is a professional new-typeSupplier of the Pharmaceutical Packaginga &Steroids Raw Materials .It's factory located in hubei province.Our company enjoyed great reputation both domestic and abroad under the belief of "Integrity management,Quality controlling and Customer orientation".The company's competitive product is Pharmaceutical Raw Materials and intermediates, In recent years, the company has made a major breakthrough in steroids raw powder.our product fit national ISO9001 and ISO2000 standards and we are usually exported to North and South America, Europe,the Middle East, Asia Pacific and Africa area, so as to establish a long-term and stable cooperation relationship with customer in the world.

Reason For Choosing Us

1) Superior Quality And Competitive Price:
Our company is a renowned pharmaceutical manufacturer with more than 15 years experiences in China and all powders are supplying from our factory directly.

2) Fast ,Safe And Well Disguised Delievery:

Well-trained and disciplined packing team and sufficient stock ensure the parcel can be delieveried to your hand fastly and safely by DHL, TNT, FedEx, HKEMS, UPS, etc.

3) Experienced In Exporting:
We have clients throughout the world. Products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries. Custome pass rate ≥99%

4) Flexible Payment Terms:
T/T,Western Union,Money Gram,Bitcoin. There will always be a term that is convient to you.

5) Warmhearted Customer Service And After-Sale Service:
The parcel's photos and tracking numbers will be sent to you once it is prepared. Any of your questions would be solved as soon as possible.

After Sales Service

1. Any inquiries will be replied within 24 hours.
2. Dedication to quality, supply & service.
3. Strictly on selecting raw materials.
4. OEM/ODM Available.
5. Reasonable & competitive price, fast lead time.
6. Sample is available for your evaluation & formulation development.

How to place an order

1. Pls tell me the items you are interested in and the order Qty, we will offer you a good price. Or you tell me your purpose (loss weight or build muscle, etc) we will tell you which is the best for you.
2. Pls tell me your shipping address so that we can tell you the shipping cost and more delivery details.
3.Then we will send you the payment information when you confirm your order.
4. Your order will be sent to the shipper immediately after your payment. And the shipper will send it out in 24 hours. You will receive the Tracking NO. in 2 days.
5. Sign for your package.
6. Kindly let me know your feedback, so that we can serve you better.

Finished Tablets

ID	Item	Capacity
1	Clenbuterol	40mcg*100/bottle
2	Clomid(Clomiphene)	50mg*100/bottle
3	Letrozle(Femara)	2.5mg*100/bottle
4	Halotestin(Fluoxymesterone)	10mg*100/bottle
5	Dianabol(Methandrostenolone)	10mg*100/bottle
6	Dianabol(Methandrostenolone)	20mg*100/bottle
7	Dianabol(Methandrostenolone)	50mg*100/bottle
8	Proviron(Mesterolone)	10mg*100/bottle
9	Proviron(Mesterolone)	25mg*100/bottle
10	Primobolan(Methenolone Acetate)	10mg*100/bottle
11	Primobolan(Methenolone Acetate)	25mg*100/bottle
12	Primobolan(Methenolone Acetate)	50mg*100/bottle
13	Superdrol(Methasterone)	10mg*100/bottle
14	T3(Liothytonine Sodium)	25mcg*100/bottle
15	T3(Liothytonine Sodium)	40mcg*100/bottle
16	T4	40mcg*100/bottle
17	Anavar(Oxandrolone)	10mg*100/bottle
18	Anavar(Oxandrolone)	25mg*100/bottle
19	Anavar(Oxandrolone)	50mg*100/bottle
20	Anadrol(Oxymetholone)	50mg*100/bottle
21	Winstrol(Stanozolol)	10mg*100/bottle
22	Winstrol(Stanozolol)	20mg*100/bottle
23	Winstrol(Stanozolol)	50mg*100/bottle
24	Turinabol(Chlordehydromethyltestosterone)	10mg*100/bottle
25	Turinabol(Chlordehydromethyltestosterone)	25mg*100/bottle
26	Nolvadex(Tamoxifen)	10mg*100/bottle
27	Nolvadex(Tamoxifen)	20mg*100/bottle
28	Aromasin(Exemestane)	25mg*100/bottle
29	Arimidex(Anastrozole)	1mg*100/bottle
30	Viagra(Sildenafil)	100mg*100/bottle
31	Cialis(Tadanafil)	20mg*100/bottle

Sarms Finished Tablets

ID	Item	Capacity
1	MK677	10mg*100/bottle
2	LGD4033	10mg*100/bottle
3	SR9009	10mg*100/bottle
4	RAD140	10mg*100/bottle
5	MK2866	10mg*100/bottle
6	AICAR	10mg*100/bottle
7	Andarine	10mg*100/bottle
8	GW-501516	10mg*100/bottle
9	YK11	10mg*100/bottle

FAQ

Q1: Have your Product Quality been Approved by the Third Party Lab?
A: Yes, all the products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.
Q2: How do you treat quality complaint?
A: First of all, our QC department will do the strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is a real quality problem, caused by us, we will send you free goods for replacement or refund your loss.
Q3: Do you Accept Sample Order?
A: Yes, we can accept small order from 10g, 100g and 1kg for your evaluation quality of our goods.
Q4: Is there any discount?
A: Yes, for the larger quantity, we always support with better price for our further cooperation.
Q5: Do you accept VISA business credit card?
A: Sorry we don't accept VISA credit card, but we'd like to accept the bank transfer, Western Union, Paypal or Bitcoin.
Q6: How long does it take the goods to arrive?
It is Depending on your location,
For the small order, please expect the 5-7 days by DHL,UPS,TNT, FEDEX, EMS and so on.
For the mass order, please allow the 5-8 days by Air or 20-35 days by Sea.
Q7: Do you have any reshipment policy?
Of course, we have the good after-sale service and re-shipment policy if the parcel lose.
Our long association with our clients has brought great benefits, we always take the upmost care in the packaging of our products. Our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts, it is still possible will seize a small number of packages. In this circumstance we promise reship free to establish a long term relationship with each other.
Q8: Can I get a sample?
A: Of course. For most products, we can provide you a free sample to test the quality, while the shipping cost should be undertook by your side.
We have formed a technology and management team that cooperate closely with some overseas Labs all speak highly of our safe shipping and goods.
please do not hesitate to contact us.